NASA Spaceline Current Awareness List #1,129 20 December 2024 (Space Life Science Research Results) -

The abstract is linked in PubMed or on the publisher’s website when available and will open in a new window.

Shirah B, Overbey EG, Fox J, Hirschberg JW, Kim J, Ryon K, Proszynski J, Meydan C, Najjar D, Collier P, LeRoy E, Pandya S, Gonzalez Y, Persad AH, Ahmad MM, Bukhari H, Naseer MI , Ashmemri MN, Taylor L, Al-Turki TM, Klotz R, Yu M, Sen J, Bailey SM, Mason. bad.Telomere length dynamics associated with short-duration human spaceflight.In: Shira B, ed. Neuroscience research in short-duration human spaceflight. Academic Press, 2025. p. 125-43.Bye: PI: C. MasonFinancing: PI indicates funding from NASA Grant No. 80NSSC23K0832 and No. NNX14AH50G.

Elsangedy E, Yamaleyeva DN, Edenhoffer NP, Deak A, Soloshenko A, Ray J, Sun JS, Yamalieva LM.Sex-specific cardiovascular adaptations to simulated microgravity in Sprague-Dawley rats.Microgravity npj. 2024 Dec 19;10(1):110.PIs: JS Willie, A. RoncaNote: Hindlimb unloading study. This article may be obtained online at no charge.

Journal Impact Factor: 5.1

Financing: JS Willey reports NASA grant funding #NNX15AB50G. A. Ronca is affiliated with NASA Ames Research Center.

Adanti RJ, Kleese H, Wachter R, Bengtsson J, Drane DL, Perez Caban J.Context knowledge is a third type of episodic memory that differs from knowing and remembering items.iScience. 2024 Dec 20;27(12):111439.Note: This article may be obtained online at no charge.

Journal Impact Factor: 4.6

Financing: Financial support for this work came from the National Institutes of Health (NIH), which included grants 2 L30 NS112849-03, 2 L30 NS112849-02, and 1 L30 NS112849-01 awarded to RJA from the National Institute of Neurological Disorders and Stroke (NINDS). Florida Institute of Technology (FIT) awards to the RJA Institutional Research Incentives (IRI) Program Authors Florida Dean of Technology Office of Dr. Marco Carvalho generously provided direct funds to support the project. DLD received support from grants R01 NS124585 from NIH/NINDS and A1321808 from Medtronic, Inc. and JPC and RJA received support from a NASA/FL Space Consortium grant.

Weiss H, Sterling L.Augmented reality evaluations to support human spaceflight performance evaluation.Aerosp Med Home Performance. 2024 Nov;95(11):831-40.Bye: to. SterlingNote: From the abstract: “As next-generation space exploration missions require increasing independence from crews, real-time diagnosis of astronaut health and performance is essential for mission operations, especially to determine readiness for extravehicular activities. An augmented reality (AR) system may be a viable tool The application allows the 3D visual signal to replace the physical objects used in traditional assessments.

Journal Impact Factor: 0.889

Financing: PI reports NASA grant funding number 80NSSC20K0409.

Zero M, Klaus D, Arquilla K, Fanchiang C.Determine and measure the operational status of crew members for spaceflight operations.Aerosp Med Home Performance. 2024 Dec;95(12):919-29. review.Bye: C. FanxiangNote: This article may be obtained online at no charge.

Journal Impact Factor: 0.889

Financing: PI reports on funding for “HCAAM VNSCOR: Using the Human Capabilities Framework to Define Crew Task Performance in Human-Automated Systems.”

Bergstrom AR, Glimm MG, Houske EA, Cooper G, Viles E, Chapman M, Bourekis K, Welhaven HD, Brahmachary PP, Hahn AK, June RK.Metabolic profiles of encapsulated chondrocytes exposed to short-term simulated microgravity.Ann Biomed Eng. 2024 December 18.Note: A rotating wall vessel was used in this study. This article may be obtained online at no charge.

Journal Impact Factor: 3.0

Financing: “The research reported in this publication was supported by the M. J. Murdock Charitable Fund under Award Number FSU-2017207 (AKH), the National Aeronautics and Space Administration under Award Number 80NSSC20M0042 (AKH), the National Science Foundation under Award Number CMMI 1554708 (RKJ), and the National Institutes of To Health under Award Numbers R01AR073964 (RKJ) the mass spectrometry facility used in this publication was funded Thanks to the MJ Murdock Charitable Trust, National Institute of General Medical Sciences of the National Institutes of Health (P20GM103474 and S10OD28650).”

Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleinedam L, Wagner M, Neher. JJ, Cunningham C, Singraw SK, Prinz M, Glass CK, Schlaschitzky JCM, Butowski O, Kleiman K, de Jaeger BL, Scheplich H, Brown JC, Landreth G, Moutinho M, Grotzindler G, Gomes. -Nicola D, McManus RM, Anderson K, Ising C, Karabaj D, Baker DJ, Laidlaw SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Dorothée G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O’Banion MK, Steinert JR, Feinstein DL, Suster M, Bhaskar K, Hong S, Schaefer DP, Gould T, Ransohoff. RM, Morgan D, Breitner J, Mancuso R, Richers SP.Neuroinflammation in Alzheimer’s disease.Nat Rev Immunol. 2024 December 9.Bye: MK O’BanionNote: This article may be obtained online at no charge.

Journal Impact Factor: 67.7

Financing: “…MKO is supported by grant 80NSSC21K0542 from NASA. …”

Picholetti PK, Duke LP, Smith AL, Klaus DM, Amick RZ.Survey and evaluation of “smart” technologies to identify potential applications for human deep space exploration missions.Acta astronaut. 2024 Sep 1;222:534-49.Note: From the summary: “Human exploration of Mars and beyond will require unprecedented levels of self-sufficiency due to the very long distances from Earth and the long mission duration. As such, astronaut crews must be able to operate in a progressively autonomous manner, as they will no longer be able to rely on Timely logistics and/or operational guidance from ground mission support teams One way to increase autonomy is to integrate intelligent (i.e., smart) technologies into mission engineering and habitat design.

Journal Impact Factor: 3.1

Financing: “This study was funded by NASA’s Human Research Program and conducted as part of the Human Health and Performance Contract [grant number NNJ15HK11B] at NASA’s Johnson Space Center and is also supported by NASA as part of NASA’s Space Technology Research Institute’s (STRI) Enhanced Habitats for Exploration Missions (HOME) “SmartHab” project. [grant number 80NSSC19K1052]”.

Picholti PK, Klaus DM.A systems approach to characterizing human deep space mission anomaly response capabilities and functional limitations.SAF Engineer Space. 2024 Dec;11(4):550-63.Note: From the abstract: “Human exploration of Mars and beyond will require unprecedented levels of onboard self-sufficiency due to very long distances from Earth and long mission durations. This paradigm shift will require the development of new anomaly response architectures to adequately protect future crews from anomalies and failures. In this In the paper, we present and illustrate the process of identifying and evaluating the main factors that influence the anomaly response process in deep space operations

Journal Impact Factor: 1.0

Financing: This study was funded by NASA under Grant No. 80NSSC19K1052 as part of the “SmartHab” project of the NASA Space Technology Research Institute (STRI).